AC Milan's Scudetto credentials will be tested when they come up against a strong Roma team on Saturday night.
Juventus, Lazio and Napoli each have 30 points in joint second and are trying to keep the pressure on Milan.
Juve are unbeaten in 12 league games and visit Chievo on Sunday.
Lazio, meanwhile, will be keen to bounce back from last weekend's 2-1 defeat at Juve when they take on Udinese in Rome.